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Can Benzoyl peroxide really cause a tumor?
Hi, I heard online that Benzoyl peroxide can cause tumors. Is this true?
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Benzoyl peroxide generates free radicals in the skin. Its effect is similar to unprotected sun exposure. The redness of the skin (erythema), caused by sun exposure and benzoyl peroxide, is the result of free radicals (oxidative stress) upon the skin. Repeated sun exposure or benzoyl peroxide use generates free radicals that damage the skin’s structure and cellular DNA, resulting in premature aging of the skin. The extent of the damage and aging from benzoyl peroxide is determined by the concentration of benzoyl peroxide, the frequency of application, and the duration of its use.
Because benzoyl peroxide generates free radicals, it interferes with and slows the healing process. The red and brown marks that are a part of the acne healing process may last weeks longer when benzoyl peroxide is a regular part of the daily regimen.
Benzoyl peroxide has been linked to cancer for a number of years and many research journal entries state "benzoyl peroxide is a free radical-generating skin tumor promoting agent." Performing a word search of the words "benzoyl peroxide cancer" in PubMed in the National Library of Medicine produces 102 articles from medical publications dealing with research aspects of benzoyl peroxide and cancer. About two-thirds of the research supports linkage between benzoyl peroxide and skin cancer.
"In 1995 the FDA changed benzoyl peroxide from a Category I (safe) to a Category III (safety is uncertain) ingredient and stated this action (56 FR 37622) was based on new information that raised a safety concern regarding benzoyl peroxide as a tumor promoter in mice …" Additionally the FDA charged manufacturers with the responsibility of providing this information to consumers so they could make educated decisions. A more complete FDA statement is at the bottom of this page, for your reference.
ive never heard that before
i dont think its true ..
I would think it has something to do with the percentage used in the mice and the amount that percentage is in humans,
I have nver heard that before..